Medicine ... in mice ....

The failure of experimental drugs that had once looked promising could have been prevented with better animal studies, according to a re-examination of past clinical trials.
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[W]ork to discover how relevant animal models are to human disease — such as Perrin’s studies on TDP43 mice — is expensive and unrewarding for researchers and their teams. Perrin argues that they must be funded specifically, perhaps by private–public collaborations.
“Somebody has to do this, or else we're wasting precious resources,” says Perrin.