… no matter what may be said against [religion] on evidential grounds, it must be manifest that [it has] conditioned the thinking of mankind since the infancy of the race. … dismissing the thing itself as a mere aberration is a proceeding that is far more lofty than sensible. What has been so powerful in its effects upon human history deserves sober study, whether it be an aberration or not.
I know that Mencken had friends among the Jesuits. One of my own Jesuit preceptors used to accompany another, older Jesuit, who had known Mencken for years, on visits to the great man in the hospital near the end of his life.