COVID-19 was regarded as an emergency, so the U.S. Food and Drug Administration skipped the approval process for use of the newly developed vaccines under Emergency Use Authorization. It can be said that the designs of the spike protein-based vaccines were also rushed. The COVID-19 vaccines are the only vaccines in history that were developed and distributed in the midst of a pandemic. All the other vaccines took years to be designed, tested, and approved.
Saturday, January 22, 2022
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…Pandemic Lessons Learned: Rushed COVID Vaccines.
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No, the first generation of vaccines isn't perfect. The critical question is, have these vaccines helped or hindered pandemic response? The answer to this question is complex, and not just a scientific matter.
ReplyDeleteWhat I take from the T-cell research is that second and later generation vaccines may need to target other proteins of the virus (and its variants), not just spike proteins. Such is good science! It's not static, nor is it meant to be.
A couple of relevant links. I suggest reading the actual research reports:
https://www.nature.com/articles/s41467-021-27
https://www.sciencemediacentre.org/expert-reaction-to-study-looking-at-cross-reactivity-of-t-cells-from-common-colds-and-protection-against-sars-cov-2-infection/
https://www.sciencemediacentre.org/expert-reaction-to-press-release-discussing-early-data-from-a-phase-1-study-coral-boost-of-a-t-cell-enhanced-self-amplifying-mrna-samrna-covid-19-vaccine-candidate-after-two-doses-of-astrazeneca/